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Document type:
journal article 
Author(s):
Ludolph, AG; Kassubek, J; Schmeck, K; Glaser, C; Wunderlich, A; Buck, AK; Reske, SN; Fegert, JM; Mottaghy, FM 
Title:
Dopaminergic dysfunction in attention deficit hyperactivity disorder (ADHD), differences between pharmacologically treated and never treated young adults: a 3,4-dihdroxy-6-[18F]fluorophenyl-l-alanine PET study. 
Abstract:
The dopaminergic system plays a key role in attention-deficit/hyperactivity disorder (ADHD). Methylphenidate (MP), a dopamine (DA) reuptake inhibitor, is a drug of first choice for treating ADHD. This cross-over study investigated alterations in DA metabolism in young males with ADHD who had never been pharmacologically treated and MP-treated patients in comparison to healthy subjects. Dynamic 3,4-dihdroxy-6-[18F]fluorophenyl-L-alanine (FDOPA) PET scans were carried out on 20 male patients with...    »
 
Journal title abbreviation:
Neuroimage 
Year:
2008 
Journal volume:
41 
Journal issue:
Pages contribution:
718-27 
Language:
eng 
Print-ISSN:
1053-8119 
TUM Institution:
Nuklearmedizinische Klinik und Poliklinik