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Document type:
journal article 
Author(s):
Miederer, M; Henriksen, G; Alke, A; Mossbrugger, I; Quintanilla-Martinez, L; Senekowitsch-Schmidtke, R; Essler, M 
Title:
Preclinical evaluation of the alpha-particle generator nuclide 225Ac for somatostatin receptor radiotherapy of neuroendocrine tumors. 
Abstract:
PURPOSE: Peptide receptor radionuclide therapy (PRRT) using somatostatin analogues labeled with beta-particle-emitting isotopes such as 90Y or 177Lu has been a promising treatment strategy for metastasized neuroendocrine tumors. Although remission can be accomplished in a high percentage of neuroendocrine tumors, some tumors do not respond to this treatment. alpha-Emitting isotopes-such as the 10-day half-life alpha-emitting generator nuclide Actinum-225 (225Ac)-are characterized by extremely hi...    »
 
Journal title abbreviation:
Clin Cancer Res 
Year:
2008 
Journal volume:
14 
Journal issue:
11 
Pages contribution:
3555-61 
Language:
eng 
Print-ISSN:
1078-0432 
TUM Institution:
Nuklearmedizinische Klinik und Poliklinik