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Document type:
Comment; Journal Article 
Author(s):
Gorlach, A; Bonello, S 
Title:
The cross-talk between NF-kappaB and HIF-1: further evidence for a significant liaison. 
Abstract:
HIF-1 (hypoxia-inducible factor-1) has been shown to essentially control the cellular response to hypoxia. Hypoxia stabilizes the inducible alpha-subunit, preventing post-translational hydroxylation and subsequent degradation via the proteasome. In recent years, clear evidence has emerged that HIF-1alpha is also responsive to many stimuli under normoxic conditions, including thrombin, growth factors, vasoactive peptides, insulin, lipopolysaccharide and cytokines such as TNF-alpha (tumour necrosi...    »
 
Journal title abbreviation:
Biochem J 
Year:
2008 
Journal volume:
412 
Journal issue:
Pages contribution:
e17-9 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
0264-6021 
TUM Institution:
Klinik für Kinderkardiologie und angeborene Herzfehler (Prof. Hess)