Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Görlach, A; Bonello, S 
Titel:
The cross-talk between NF-kappaB and HIF-1: further evidence for a significant liaison. 
Abstract:
HIF-1 (hypoxia-inducible factor-1) has been shown to essentially control the cellular response to hypoxia. Hypoxia stabilizes the inducible alpha-subunit, preventing post-translational hydroxylation and subsequent degradation via the proteasome. In recent years, clear evidence has emerged that HIF-1alpha is also responsive to many stimuli under normoxic conditions, including thrombin, growth factors, vasoactive peptides, insulin, lipopolysaccharide and cytokines such as TNF-alpha (tumour necrosi...    »
 
Zeitschriftentitel:
Biochem J 
Jahr:
2008 
Band / Volume:
412 
Heft / Issue:
Seitenangaben Beitrag:
e17-9 
Sprache:
eng 
Print-ISSN:
0264-6021 
TUM Einrichtung:
r Kinderkardiologie und angeborene Herzfehler