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Dokumenttyp:
journal article 
Autor(en):
Dank, M; Zaluski, J; Barone, C; Valvere, V; Yalcin, S; Peschel, C; Wenczl, M; Goker, E; Cisar, L; Wang, K; Bugat, R 
Titel:
Randomized phase III study comparing irinotecan combined with 5-fluorouracil and folinic acid to cisplatin combined with 5-fluorouracil in chemotherapy naive patients with advanced adenocarcinoma of the stomach or esophagogastric junction. 
Abstract:
BACKGROUND: We aimed to establish the superiority (or noninferiority if superiority was not achieved) in terms of time to progression (TTP) of irinotecan/5-fluorouracil (IF) over cisplatin/5-fluorouracil (CF) in chemonaive patients with adenocarcinoma of the stomach/esophagogastric junction. PATIENTS AND METHODS: Patients received either IF: i.v. irinotecan 80 mg/m(2) 30 min, folinic acid 500 mg/m(2) 2 h, 5-fluorouracil (5-FU) 2000 mg/m(2) 22 h, for 6/7 weeks or CF: cisplatin 100 mg/m(2) 1-3 h,...    »
 
Zeitschriftentitel:
Ann Oncol 
Jahr:
2008 
Band / Volume:
19 
Heft / Issue:
Seitenangaben Beitrag:
1450-7 
Sprache:
eng 
Print-ISSN:
0923-7534 
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik