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Dokumenttyp:
journal article 
Autor(en):
Ruland, J 
Titel:
CARD9 signaling in the innate immune response. 
Abstract:
CARD9 is a caspase recruitment domain-containing signaling protein that is highly expressed in dendritic cells and in macrophages. Work over the last two years has identified CARD9 as a central regulator of innate immunity. Best characterized is CARD9's function downstream of ITAM-bearing or ITAM-coupled receptors in myeloid cells, including its essential role downstream of the antifungal pattern-recognition receptor Dectin-1. In the ITAM receptor pathway, CARD9 couples receptor proximal splenic...    »
 
Zeitschriftentitel:
Ann N Y Acad Sci 
Jahr:
2008 
Band / Volume:
1143 
Seitenangaben Beitrag:
35-44 
Sprache:
eng 
Print-ISSN:
0077-8923 
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik