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Document type:
journal article 
Author(s):
Maier, KL; Alessandrini, F; Beck-Speier, I; Hofer, TP; Diabaté, S; Bitterle, E; Stöger, T; Jakob, T; Behrendt, H; Horsch, M; Beckers, J; Ziesenis, A; Hültner, L; Frankenberger, M; Krauss-Etschmann, S; Schulz, H 
Title:
Health effects of ambient particulate matter--biological mechanisms and inflammatory responses to in vitro and in vivo particle exposures. 
Abstract:
In this article, we review and analyze different modes of exposure to ultrafine particles in order to assess particle-induced inflammatory responses and the underlying mechanisms in vitro and in vivo. Based on results from monocytic cells cultured under submerged conditions, we discuss (1) the impact of particle properties such as surface area and oxidative potential on lipid metabolism as a highly sensitive regulatory pathway and (2) the interference of diesel exhaust particles with toll-like r...    »
 
Journal title abbreviation:
Inhal Toxicol 
Year:
2008 
Journal volume:
20 
Journal issue:
Pages contribution:
319-37 
Language:
eng 
Print-ISSN:
0895-8378 
TUM Institution:
r Dermatologie und Allergologie