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Document type:
journal article 
Author(s):
Thierolf, M; Hagmann, ML; Pfeffer, M; Berntenis, N; Wild, N; Roessler, M; Palme, S; Karl, J; Bodenmuller, H; Ruschofi, J; Rossol, S; Rohr, G; Rosch, W; Friess, H; Eickhoff, A; Jauch, KW; Langen, H; Zolg, W; Tacke, M 
Title:
Towards a comprehensive proteome of normal and malignant human colon tissue by 2-D-LC-ESI-MS and 2-DE proteomics and identification of S100A12 as potential cancer biomarker 
Abstract:
The aim of this study was to characterize the proteome of normal and malignant colonic tissue. We previously studied the colon proteome using 2-DE and MALDI-MS and identified 734 proteins (RoeBler, M., Rollinger, W, Palme S., Hagmann, MA., et al., Chn. Cancer Res. 2005, 11, 6550-6557). Here we report the identification of additional colon proteins from the same set of tissue samples using a complementary nano-flow 2-D-LC-ESI-MS. In total, 484 proteins were identified in colon. Of these, 252 had...    »
 
Journal title abbreviation:
Proteomics Clin Appl 
Year:
2008 
Journal volume:
Journal issue:
Pages contribution:
11-22 
Language:
eng 
Print-ISSN:
1862-8346 
TUM Institution:
Chirurgiesche Klinik und Poliklinik