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Dokumenttyp:
journal article 
Autor(en):
Wente, MN; Gaida, MM; Mayer, C; Michalski, CW; Haag, N; Giese, T; Felix, K; Bergmann, F; Giese, NA; Friess, H 
Titel:
Expression and potential function of the CXC chemokine CXCL16 in pancreatic ductal adenocarcinoma. 
Abstract:
CXC chemokines have a major influence on the angiogenesis, growth and metastatic potential of pancreatic ductal adenocarcinoma. CXCL16 is a unique transmembrane CXC chemokine, which is shed by members of the disintegrins and metalloproteases (ADAMs), in particular by ADAM10 and ADAM17. In our study, we evaluated expression and potential function of CXCL16 and its receptor CXCR6. CXCL16 and the receptor CXCR6 are upregulated in pancreatic ductal adenocarcinoma (PDAC) and chronic pancreatitis tiss...    »
 
Zeitschriftentitel:
Int J Oncol 
Jahr:
2008 
Band / Volume:
33 
Heft / Issue:
Seitenangaben Beitrag:
297-308 
Sprache:
eng 
Print-ISSN:
1019-6439 
TUM Einrichtung:
Chirurgiesche Klinik und Poliklinik