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Document type:
journal article 
Author(s):
Wente, MN; Gaida, MM; Mayer, C; Michalski, CW; Haag, N; Giese, T; Felix, K; Bergmann, F; Giese, NA; Friess, H 
Title:
Expression and potential function of the CXC chemokine CXCL16 in pancreatic ductal adenocarcinoma. 
Abstract:
CXC chemokines have a major influence on the angiogenesis, growth and metastatic potential of pancreatic ductal adenocarcinoma. CXCL16 is a unique transmembrane CXC chemokine, which is shed by members of the disintegrins and metalloproteases (ADAMs), in particular by ADAM10 and ADAM17. In our study, we evaluated expression and potential function of CXCL16 and its receptor CXCR6. CXCL16 and the receptor CXCR6 are upregulated in pancreatic ductal adenocarcinoma (PDAC) and chronic pancreatitis tiss...    »
 
Journal title abbreviation:
Int J Oncol 
Year:
2008 
Journal volume:
33 
Journal issue:
Pages contribution:
297-308 
Language:
eng 
Print-ISSN:
1019-6439 
TUM Institution:
Chirurgiesche Klinik und Poliklinik