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Document type:
journal article 
Author(s):
Nordlinger, B; Sorbye, H; Glimelius, B; Poston, GJ; Schlag, PM; Rougier, P; Bechstein, WO; Primrose, JN; Walpole, ET; Finch-Jones, M; Jaeck, D; Mirza, D; Parks, RW; Collette, L; Praet, M; Bethe, U; Van Cutsem, E; Scheithauer, W; Gruenberger, T; EORTC Gastro-Intestinal Tract Cancer Group; Cancer Research UK; Arbeitsgruppe Lebermetastasen und-tumoren in der Chirurgischen Arbeitsgemeinschaft Onkologie (ALM-CAO); Australasian Gastro-Intestinal Trials Group (AGITG); Fédération Francophone de Cancérol...    »
 
Title:
Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial. 
Abstract:
BACKGROUND: Surgical resection alone is regarded as the standard of care for patients with liver metastases from colorectal cancer, but relapse is common. We assessed the combination of perioperative chemotherapy and surgery compared with surgery alone for patients with initially resectable liver metastases from colorectal cancer. METHODS: This parallel-group study reports the trial's final data for progression-free survival for a protocol unspecified interim time-point, while overall survival i...    »
 
Journal title abbreviation:
Lancet 
Year:
2008 
Journal volume:
371 
Journal issue:
9617 
Pages contribution:
1007-16 
Language:
eng 
Print-ISSN:
0140-6736 
TUM Institution:
Chirurgiesche Klinik und Poliklinik