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Document type:
journal article 
Author(s):
Vallabhapurapu, S; Powolny-Budnicka, I; Riemann, M; Schmid, RM; Paxian, S; Pfeffer, K; Körner, H; Weih, F 
Title:
Rel/NF-kappaB family member RelA regulates NK1.1- to NK1.1+ transition as well as IL-15-induced expansion of NKT cells. 
Abstract:
Development of NKT cells was shown to depend on lymphotoxin (LT) and IL-15 signaling pathways as well as on cytokine receptor common gamma chain. After positive selection, NKT-cell precursors transit through progressive maturation stages including proliferative expansion within the NK1.1(-) window. The transcription factors that integrate different signaling pathways into different stages of NKT-cell development are not well characterized. Here, we show that the Rel/NF-kappaB family member RelA...    »
 
Journal title abbreviation:
Eur J Immunol 
Year:
2008 
Journal volume:
38 
Journal issue:
12 
Pages contribution:
3508-19 
Language:
eng 
Print-ISSN:
0014-2980 
TUM Institution:
II. Medizinische Klinik und Poliklinik