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Document type:
journal article 
Author(s):
Frank, B; Burwinkel, B; Bermejo, JL; Försti, A; Hemminki, K; Houlston, R; Mangold, E; Rahner, N; Friedl, W; Friedrichs, N; Buettner, R; Engel, C; Loeffler, M; Holinski-Feder, E; Morak, M; Keller, G; Schackert, HK; Krüger, S; Goecke, T; Moeslein, G; Kloor, M; Gebert, J; Kunstmann, E; Schulmann, K; Rüschoff, J; Propping, P; German HNPCC Consortium 
Title:
Ten recently identified associations between nsSNPs and colorectal cancer could not be replicated in German families. 
Abstract:
Ten non-synonymous single nucleotide polymorphisms (nsSNPs), which were recently associated with colorectal cancer risk in a comprehensive, array based study (AKAP9 M463I, DKK3 G335R, AMPD1 Q12X, LIPC L356F, PSMB9 V32I, THBS1 N700S, CA6 S90G, ASCC3 C1995S, DHX36 S416C and CPA4 G303C) were re-evaluated in the present study based on 626 German familial non-HNPCC colorectal cancer patients and 736 healthy controls. No associations of any of the 10 nsSNPs with colorectal cancer could be replicated....    »
 
Journal title abbreviation:
Cancer Lett 
Year:
2008 
Journal volume:
271 
Journal issue:
Pages contribution:
153-7 
Language:
eng 
Print-ISSN:
0304-3835 
TUM Institution:
Institut für Allgemeine Pathologie und pathologische Anatomie