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Document type:
journal article 
Author(s):
Adhikary, D; Behrends, U; Feederle, R; Delecluse, HJ; Mautner, J 
Title:
Standardized and highly efficient expansion of Epstein-Barr virus-specific CD4+ T cells by using virus-like particles. 
Abstract:
Epstein-Barr virus (EBV)-specific T-cell lines generated by repeated stimulation with EBV-immortalized lymphoblastoid B-cell lines (LCL) have been successfully used to treat EBV-associated posttransplant lymphoproliferative disease (PTLD) in hematopoietic stem cell transplant recipients. However, PTLD in solid-organ transplant recipients and other EBV-associated malignancies respond less efficiently to this adoptive T-cell therapy. LCL-stimulated T-cell preparations are polyclonal and contain CD...    »
 
Journal title abbreviation:
J Virol 
Year:
2008 
Journal volume:
82 
Journal issue:
Pages contribution:
3903-11 
Language:
eng 
Print-ISSN:
0022-538X 
TUM Institution:
Kinderklinik und Poliklinik