User: Guest  Login
Document type:
journal article 
Author(s):
Lage, H; Surowiak, P; Holm, PS 
Title:
[YB-1 as a potential target in cancer therapy] 
Abstract:
The 42-kDa multifunctional cellular protein Y-box protein 1 (YB-1) is expressed in various cancers. It is localized in the cytoplasm as well as in the nucleus. In particular, YB-1 is localized in the nuclear compartment following cellular stress, such as radiation, drug treatment, hyperthermia, or viral infection. Within the nucleus, YB-1 can act as a transcription factor, and it is involved in the regulation of important cancer-associated genes. For example, YB-1 triggers the expression of Her-...    »
 
Journal title abbreviation:
Pathologe 
Year:
2008 
Journal volume:
29 Suppl 2 
Pages contribution:
187-90 
Language:
de 
Print-ISSN:
0172-8113 
TUM Institution:
Institut für experimentelle Onkologie und Therapieforschung