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Document type:
journal article 
Author(s):
Mykhaylyk, O; Zelphati, O; Rosenecker, J; Plank, C 
Title:
siRNA delivery by magnetofection. 
Abstract:
Magnetofection is defined as the magnetically enhanced delivery of nucleic acids associated with magnetic nanoparticles and has been utilized to deliver synthetic siRNAs to cultured cells. Certain magnetic nanomaterials associate with siRNAs and are suitable for siRNA delivery, either alone or in combination with cationic polymers or cationic lipid enhancers; these complexes are targeted to the cell surface by application of a gradient magnetic field. In this review methods are described to exa...    »
 
Journal title abbreviation:
Curr Opin Mol Ther 
Year:
2008 
Journal volume:
10 
Journal issue:
Pages contribution:
493-505 
Language:
eng 
Print-ISSN:
1464-8431 
TUM Institution:
Institut für experimentelle Onkologie und Therapieforschung