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Dokumenttyp:
journal article 
Autor(en):
Mykhaylyk, O; Zelphati, O; Rosenecker, J; Plank, C 
Titel:
siRNA delivery by magnetofection. 
Abstract:
Magnetofection is defined as the magnetically enhanced delivery of nucleic acids associated with magnetic nanoparticles and has been utilized to deliver synthetic siRNAs to cultured cells. Certain magnetic nanomaterials associate with siRNAs and are suitable for siRNA delivery, either alone or in combination with cationic polymers or cationic lipid enhancers; these complexes are targeted to the cell surface by application of a gradient magnetic field. In this review methods are described to exa...    »
 
Zeitschriftentitel:
Curr Opin Mol Ther 
Jahr:
2008 
Band / Volume:
10 
Heft / Issue:
Seitenangaben Beitrag:
493-505 
Sprache:
eng 
Print-ISSN:
1464-8431 
TUM Einrichtung:
r experimentelle Onkologie und Therapieforschung