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Document type:
journal article 
Author(s):
Bleifuss, E; Bendz, H; Sirch, B; Thompson, S; Brandl, A; Milani, V; Graner, MW; Drexler, I; Kuppner, M; Katsanis, E; Noessner, E; Issels, RD 
Title:
Differential capacity of chaperone-rich lysates in cross-presenting human endogenous and exogenous melanoma differentiation antigens. 
Abstract:
The goal of immune-based tumor therapies is the activation of immune cells reactive against a broad spectrum of tumor-expressed antigens. Vaccines based on chaperone proteins appear promising as these proteins naturally exist as complexes with various protein fragments including those derived from tumor-associated antigens. Multi-chaperone systems are expected to have highest polyvalency as different chaperones can carry distinct sets of antigenic fragments. A free-solution isoelectric focusing...    »
 
Journal title abbreviation:
Int J Hyperthermia 
Year:
2008 
Journal volume:
24 
Journal issue:
Pages contribution:
623-37 
Language:
eng 
Print-ISSN:
0265-6736 
TUM Institution:
Institut für Virologie