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Dokumenttyp:
journal article 
Autor(en):
Schulze, K; Staib, C; Schätzl, HM; Ebensen, T; Erfle, V; Guzman, CA 
Titel:
A prime-boost vaccination protocol optimizes immune responses against the nucleocapsid protein of the SARS coronavirus. 
Abstract:
Severe acute respiratory syndrome (SARS) is a serious infectious disease caused by the SARS coronavirus. We assessed the potential of prime-boost vaccination protocols based on the nucleocapsid (NC) protein co-administered with a derivative of the mucosal adjuvant MALP-2 or expressed by modified Vaccinia virus Ankara (MVA-NC) to stimulate humoral and cellular immune responses at systemic and mucosal levels. The obtained results demonstrated that strong immune responses can be elicited both at sy...    »
 
Zeitschriftentitel:
Vaccine 
Jahr:
2008 
Band / Volume:
26 
Heft / Issue:
51 
Seitenangaben Beitrag:
6678-84 
Sprache:
eng 
Print-ISSN:
0264-410X 
TUM Einrichtung:
r Virologie