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Dokumenttyp:
journal article 
Autor(en):
Boltze, J; Förschler, A; Nitzsche, B; Waldmin, D; Hoffmann, A; Boltze, CM; Dreyer, AY; Goldammer, A; Reischauer, A; Härtig, W; Geiger, KD; Barthel, H; Emmrich, F; Gille, U 
Titel:
Permanent middle cerebral artery occlusion in sheep: a novel large animal model of focal cerebral ischemia. 
Abstract:
As effective stroke treatment by thrombolysis is bound to a narrow time window excluding most patients, numerous experimental treatment strategies have been developed to gain new options for stroke treatment. However, all approaches using neuroprotective agents that have been successfully evaluated in rodents have subsequently failed in clinical trials. Existing large animal models are of significant scientific value, but sometimes limited by ethical drawbacks and mostly do not allow for long-te...    »
 
Zeitschriftentitel:
J Cereb Blood Flow Metab 
Jahr:
2008 
Band / Volume:
28 
Heft / Issue:
12 
Seitenangaben Beitrag:
1951-64 
Sprache:
eng 
Print-ISSN:
0271-678X 
TUM Einrichtung:
r Neuroradiologie