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Dokumenttyp:
journal article 
Autor(en):
He, C; Hu, H; Braren, R; Fong, SY; Trumpp, A; Carlson, TR; Wang, RA 
Titel:
c-myc in the hematopoietic lineage is crucial for its angiogenic function in the mouse embryo. 
Abstract:
The c-myc proto-oncogene, which is crucial for the progression of many human cancers, has been implicated in key cellular processes in diverse cell types, including endothelial cells that line the blood vessels and are critical for angiogenesis. The de novo differentiation of endothelial cells is known as vasculogenesis, whereas the growth of new blood vessels from pre-existing vessels is known as angiogenesis. To ascertain the function of c-myc in vascular development, we deleted c-myc in selec...    »
 
Zeitschriftentitel:
Development 
Jahr:
2008 
Band / Volume:
135 
Heft / Issue:
14 
Seitenangaben Beitrag:
2467-77 
Sprache:
eng 
Print-ISSN:
0950-1991 
TUM Einrichtung:
r Radiologie