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Document type:
journal article 
Author(s):
He, C; Hu, H; Braren, R; Fong, SY; Trumpp, A; Carlson, TR; Wang, RA 
Title:
c-myc in the hematopoietic lineage is crucial for its angiogenic function in the mouse embryo. 
Abstract:
The c-myc proto-oncogene, which is crucial for the progression of many human cancers, has been implicated in key cellular processes in diverse cell types, including endothelial cells that line the blood vessels and are critical for angiogenesis. The de novo differentiation of endothelial cells is known as vasculogenesis, whereas the growth of new blood vessels from pre-existing vessels is known as angiogenesis. To ascertain the function of c-myc in vascular development, we deleted c-myc in selec...    »
 
Journal title abbreviation:
Development 
Year:
2008 
Journal volume:
135 
Journal issue:
14 
Pages contribution:
2467-77 
Language:
eng 
Print-ISSN:
0950-1991 
TUM Institution:
Institut für Radiologie