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Document type:
journal article 
Author(s):
Boddington, S; Sutton, EJ; Jones, E; Purcell, DD; Henning, TD; Tavri, S; Meier, R; Sista, A; Fu, Y; Daldrup-Link, H 
Title:
Improved fluorescence of indocyanine green in vitro and in vivo after simple cooling procedures. 
Abstract:
Indocyanine green (ICG) is a contrast agent used for detecting angiogenesis with optical imaging (OI). The purpose of this study was to investigate whether cooling procedures increase the signal yield of ICG with OI. Test samples of 0.05 and 0.02 mM ICG in 40% DMSO and 60% DMEM underwent OI at four different temperatures (5, 37, 55 and 75 degrees C). In addition, six athymic rats with an antigen-induced arthritis of the knee and ankle joints underwent OI before and after injection of ICG (10 mg/...    »
 
Journal title abbreviation:
Contrast Media Mol Imaging 
Year:
2008 
Journal volume:
Journal issue:
Pages contribution:
191-7 
Language:
eng 
Print-ISSN:
1555-4309 
TUM Institution:
Institut für Radiologie