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Document type:
journal article 
Author(s):
Rappl, A; Piontek, G; Schlegel, J 
Title:
EGFR-dependent migration of glial cells is mediated by reorganisation of N-cadherin. 
Abstract:
Receptor tyrosine kinases of the EGFR family exert their various effects on cellular function through the formation of different dimeric receptor complexes. To investigate the functional impact of EGFR-HER2 heterodimers on migration of glial tumour cells, we stably transfected different HER2 constructs, including a constitutively active (HER2VE) and a dominant-negative (HER2VEKA) receptor, in the EGFR-overexpressing human glioma cell line LN18. Interference of EGFR activation through HER2VEKA in...    »
 
Journal title abbreviation:
J Cell Sci 
Year:
2008 
Journal volume:
121 
Journal issue:
Pt 24 
Pages contribution:
4089-97 
Language:
eng 
Print-ISSN:
0021-9533 
TUM Institution:
Institut für Allgemeine Pathologie und pathologische Anatomie