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Dokumenttyp:
journal article 
Autor(en):
Rappl, A; Piontek, G; Schlegel, J 
Titel:
EGFR-dependent migration of glial cells is mediated by reorganisation of N-cadherin. 
Abstract:
Receptor tyrosine kinases of the EGFR family exert their various effects on cellular function through the formation of different dimeric receptor complexes. To investigate the functional impact of EGFR-HER2 heterodimers on migration of glial tumour cells, we stably transfected different HER2 constructs, including a constitutively active (HER2VE) and a dominant-negative (HER2VEKA) receptor, in the EGFR-overexpressing human glioma cell line LN18. Interference of EGFR activation through HER2VEKA in...    »
 
Zeitschriftentitel:
J Cell Sci 
Jahr:
2008 
Band / Volume:
121 
Heft / Issue:
Pt 24 
Seitenangaben Beitrag:
4089-97 
Sprache:
eng 
Print-ISSN:
0021-9533 
TUM Einrichtung:
r Allgemeine Pathologie und pathologische Anatomie