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Dokumenttyp:
journal article 
Autor(en):
Haghikia, A; Ladage, K; Hinkerohe, D; Vollmar, P; Heupel, K; Dermietzel, R; Faustmann, PM 
Titel:
Implications of antiinflammatory properties of the anticonvulsant drug levetiracetam in astrocytes. 
Abstract:
There is accumulating evidence that epileptic activity is accompanied by inflammatory processes. In the present study, we evaluated the effect of levetiracetam (Keppra), an anticonvulsant drug with decisive antiepileptic features, with regard to its putative antiinflammatory potential. We previously established an in vitro cell culture model to mimic inflammatory conditions: Primary astrocytic cultures of newborn rats were cocultured with 30% (M30) microglial cells. Alternatively, cocultures con...    »
 
Zeitschriftentitel:
J Neurosci Res 
Jahr:
2008 
Band / Volume:
86 
Heft / Issue:
Seitenangaben Beitrag:
1781-8 
Sprache:
eng 
Print-ISSN:
0360-4012 
TUM Einrichtung:
Neurologische Klinik und Poliklinik