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Document type:
journal article 
Author(s):
May, F; Matiasek, K; Vroemen, M; Caspers, C; Mrva, T; Arndt, C; Schlenker, B; Gais, P; Brill, T; Buchner, A; Blesch, A; Hartung, R; Stief, C; Gansbacher, B; Weidner, N 
Title:
GDNF-transduced Schwann cell grafts enhance regeneration of erectile nerves. 
Abstract:
BACKGROUND: Schwann cell-seeded guidance tubes have been shown to promote cavernous nerve regeneration, and the local delivery of neurotrophic factors may additionally enhance nerve regenerative capacity. The present study evaluates whether the transplantation of GDNF-overexpressing Schwann cells may enhance regeneration of bilaterally transected erectile nerves in rats. METHODS: Silicon tubes seeded with either GDNF-overexpressing or GFP-expressing Schwann cells were implanted into the gaps bet...    »
 
Journal title abbreviation:
Eur Urol 
Year:
2008 
Journal volume:
54 
Journal issue:
Pages contribution:
1179-87 
Language:
eng 
Print-ISSN:
0302-2838 
TUM Institution:
r experimentelle Onkologie und Therapieforschung