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Dokumenttyp:
journal article 
Autor(en):
Linsel-Nitschke, P; Götz, A; Medack, A; König, IR; Bruse, P; Lieb, W; Mayer, B; Stark, K; Hengstenberg, C; Fischer, M; Baessler, A; Ziegler, A; Schunkert, H; Erdmann, J 
Titel:
Genetic variation in the arachidonate 5-lipoxygenase-activating protein (ALOX5AP) is associated with myocardial infarction in the German population. 
Abstract:
Genetic variation in the genes ALOX5AP (arachidonate 5-lipoxygenase-activating protein) and LTA4H (leukotriene A4 hydrolase) has previously been shown to contribute to the risk of MI (myocardial infarction) and stroke in Icelandic and Scottish populations. Both genes encode proteins playing a role in the synthesis of the pro-inflammatory leukotriene B mediators, possibly providing a link between MI and inflammation. The aim of the present study was to investigate whether these associations could...    »
 
Zeitschriftentitel:
Clin Sci (Lond) 
Jahr:
2008 
Band / Volume:
115 
Heft / Issue:
10 
Seitenangaben Beitrag:
309-15 
Sprache:
eng 
Print-ISSN:
0143-5221 
TUM Einrichtung:
hrungsmedizin