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Document type:
journal article 
Author(s):
Gasteiger, G; Kastenmuller, W; Ljapoci, R; Sutter, G; Drexler, I 
Title:
Cross-priming of cytotoxic T cells dictates antigen requisites for modified vaccinia virus Ankara vector vaccines. 
Abstract:
Recombinant vaccines based on modified vaccinia virus Ankara (MVA) have an excellent record concerning safety and immunogenicity and are currently being evaluated in numerous clinical studies for immunotherapy of infectious diseases and cancer. However, knowledge about the biological properties of target antigens to efficiently induce MVA vaccine-mediated immunity in vivo is sparse. Here, we examined distinct antigen presentation pathways and different antigen formulations contained in MVA vacci...    »
 
Journal title abbreviation:
J Virol 
Year:
2007 
Journal volume:
81 
Journal issue:
21 
Pages contribution:
11925-36 
Language:
eng 
Print-ISSN:
0022-538X 
TUM Institution:
Institut für Virologie