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Document type:
journal article 
Author(s):
Tatzelt, J; Schätzl, HM 
Title:
Molecular basis of cerebral neurodegeneration in prion diseases. 
Abstract:
The biochemical nature and the replication of infectious prions have been intensively studied in recent years. Much less is known about the cellular events underlying neuronal dysfunction and cell death. As the cellular function of the normal cellular isoform of prion protein is not exactly known, the impact of gain of toxic function or loss of function, or a combination of both, in prion pathology is still controversial. There is increasing evidence that the normal cellular isoform of the prion...    »
 
Journal title abbreviation:
FEBS J 
Year:
2007 
Journal volume:
274 
Journal issue:
Pages contribution:
606-11 
Language:
eng 
Print-ISSN:
1742-464X 
TUM Institution:
Institut für Virologie