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Document type:
journal article 
Author(s):
Wiedenmann, N; Valdecanas, D; Hunter, N; Hyde, S; Buchholz, TA; Milas, L; Mason, KA 
Title:
130-nm albumin-bound paclitaxel enhances tumor radiocurability and therapeutic gain. 
Abstract:
PURPOSE: 130-nm albumin-bound paclitaxel (nab-paclitaxel) is a novel solvent-free albumin-bound paclitaxel, designed to avoid solvent-related toxicity. Nab-paclitaxel has been successfully introduced into the clinic but its radiation-enhancing potential has not yet been evaluated. We conducted a preclinical evaluation of the radiation-modulating effects of nab-paclitaxel in tumor and normal tissues. EXPERIMENTAL DESIGN: Mice bearing syngeneic ovarian or mammary carcinomas were treated with nab-p...    »
 
Journal title abbreviation:
Clin Cancer Res 
Year:
2007 
Journal volume:
13 
Journal issue:
Pages contribution:
1868-74 
Language:
eng 
Print-ISSN:
1078-0432 
TUM Institution:
Klinik und Poliklinik für Strahlentherapie und Radiologische Onkologie