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Document type:
journal article 
Author(s):
Schmitt, E; Gehrmann, M; Brunet, M; Multhoff, G; Garrido, C 
Title:
Intracellular and extracellular functions of heat shock proteins: repercussions in cancer therapy. 
Abstract:
Stress or heat shock proteins (HSPs) are the most conserved proteins present in both prokaryotes and eukaryotes. Their expression is induced in response to a wide variety of physiological and environmental insults. These proteins play an essential role as molecular chaperones by assisting the correct folding of nascent and stress-accumulated misfolded proteins, and preventing their aggregation. HSPs have a dual function depending on their intracellular or extracellular location. Intracellular HS...    »
 
Journal title abbreviation:
J Leukoc Biol 
Year:
2007 
Journal volume:
81 
Journal issue:
Pages contribution:
15-27 
Language:
eng 
Print-ISSN:
0741-5400 
TUM Institution:
Klinik und Poliklinik für Strahlentherapie und Radiologische Onkologie