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Document type:
journal article 
Author(s):
Rösner, S; Leucht, S; Lehert, P; Soyka, M 
Title:
Acamprosate supports abstinence, naltrexone prevents excessive drinking: evidence from a meta-analysis with unreported outcomes. 
Abstract:
Two pharmacological agents have repeatedly been shown to be efficacious for relapse prevention in alcohol dependence: The putative glutamate-antagonist acamprosate and the opioid-antagonist naltrexone. Clinical evidence for both drugs is based on various outcome criteria. Whereas for acamprosate primarily abstinence maintenance has been demonstrated, studies with naltrexone have mostly emphasised the prevention of heavy drinking. The remaining effects of both drugs are not always reported; acco...    »
 
Journal title abbreviation:
J Psychopharmacol 
Year:
2008 
Journal volume:
22 
Journal issue:
Pages contribution:
11-23 
Language:
eng 
Print-ISSN:
0269-8811 
TUM Institution:
r Psychiatrie und Psychotherapie