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Dokumenttyp:
journal article 
Autor(en):
Ying, SW; Jia, F; Abbas, SY; Hofmann, F; Ludwig, A; Goldstein, PA 
Titel:
Dendritic HCN2 channels constrain glutamate-driven excitability in reticular thalamic neurons. 
Abstract:
Hyperpolarization activated cyclic nucleotide (HCN) gated channels conduct a current, I(h); how I(h) influences excitability and spike firing depends primarily on channel distribution in subcellular compartments. For example, dendritic expression of HCN1 normalizes somatic voltage responses and spike output in hippocampal and cortical neurons. We reported previously that HCN2 is predominantly expressed in dendritic spines in reticular thalamic nucleus (RTN) neurons, but the functional impact of...    »
 
Zeitschriftentitel:
J Neurosci 
Jahr:
2007 
Band / Volume:
27 
Heft / Issue:
32 
Seitenangaben Beitrag:
8719-32 
Sprache:
eng 
Print-ISSN:
0270-6474 
TUM Einrichtung:
r Pharmakologie und Toxikologie