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Document type:
journal article 
Author(s):
Dongmo, AB; Azebaze, AG; Nguelefack, TB; Ouahouo, BM; Sontia, B; Meyer, M; Nkengfack, AE; Kamanyi, A; Vierling, W 
Title:
Vasodilator effect of the extracts and some coumarins from the stem bark of Mammea africana (Guttiferae). 
Abstract:
CH(2)Cl(2) fraction obtained from the stem bark of Mammea africana inhibited noradrenaline (NA) or KCl-induced contraction in isolated guinea pig and rat aorta. The vasorelaxant potency of the CH(2)Cl(2) fraction of Mammea africana was diminished by a pre-treatment with Nitro-l-arginine methyl ester (l-NAME), an inhibitor of NO synthase, which was however not affected by indomethacin pre-treatment. These findings indicated that the vasorelaxant effect of Mammea africana may be partially endothel...    »
 
Journal title abbreviation:
J Ethnopharmacol 
Year:
2007 
Journal volume:
111 
Journal issue:
Pages contribution:
329-34 
Language:
eng 
Print-ISSN:
0378-8741 
TUM Institution:
Institut für Pharmakologie und Toxikologie