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Document type:
journal article 
Author(s):
Fend, F; Horn, T; Koch, I; Vela, T; Orazi, A 
Title:
Atypical chronic myeloid leukemia as defined in the WHO classification is a JAK2 V617F negative neoplasm. 
Abstract:
Atypical chronic myeloid leukemia (aCML) as defined by the WHO classification is a rare hematopoietic stem cell disorder, which shows both myeloproliferative as well as myelodysplastic features. Because of the presence of neutrophilic leukocytosis, aCML may resemble chronic myelogenous leukemia. However, in contrast with the latter, aCML lacks a Philadelphia chromosome or the BCR/ABL fusion gene. The molecular pathogenesis of aCML and its relationship to other myeloproliferative neoplasms is unk...    »
 
Journal title abbreviation:
Leuk Res 
Year:
2008 
Journal volume:
32 
Journal issue:
12 
Pages contribution:
1931-5 
Language:
eng 
Print-ISSN:
0145-2126 
TUM Institution:
Institut für Allgemeine Pathologie und pathologische Anatomie