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Dokumenttyp:
journal article 
Autor(en):
Langer, R; Feith, M; Siewert, JR; Wester, HJ; Hoefler, H 
Titel:
Expression and clinical significance of glucose regulated proteins GRP78 (BiP) and GRP94 (GP96) in human adenocarcinomas of the esophagus. 
Abstract:
BACKGROUND: Glucose regulated proteins (GRPs) are main regulators of cellular homeostasis due to their role as molecular chaperones. Moreover, the functions of GRPs suggest that they also may play important roles in cancer biology. In this study we investigated the glucose regulated proteins GRP78 (BiP) and GRP94 (GP96) in a series of human esophageal adenocarcinomas to determine their implications in cancer progression and prognosis. METHODS: Formalin-fixed, paraffin-embedded tissues of primary...    »
 
Zeitschriftentitel:
BMC Cancer 
Jahr:
2008 
Band / Volume:
Seitenangaben Beitrag:
70 
Sprache:
eng 
TUM Einrichtung:
r Allgemeine Pathologie und pathologische Anatomie; Chirurgiesche Klinik und Poliklinik; Nuklearmedizinische Klinik und Poliklinik