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Document type:
journal article 
Author(s):
Schmitt, AM; Riniker, F; Anlauf, M; Schmid, S; Soltermann, A; Moch, H; Heitz, PU; Klöppel, G; Komminoth, P; Perren, A 
Title:
Islet 1 (Isl1) expression is a reliable marker for pancreatic endocrine tumors and their metastases. 
Abstract:
BACKGROUND: Tracing the origin of a metastasis of a neuroendocrine carcinoma is a challenge. The transcription factors Cdx2 and TTF1 have been found to be helpful in identifying well-differentiated neuroendocrine tumors of gastrointestinal and pulmonary origin, respectively. So far, such a marker is lacking for pancreatic neuroendocrine tumors (PETs) and metastases thereof. Islet1 (Isl1) is a transcription factor expressed in pancreatic islet cells. The aim of this study was (1) to test the spec...    »
 
Journal title abbreviation:
Am J Surg Pathol 
Year:
2008 
Journal volume:
32 
Journal issue:
Pages contribution:
420-5 
Language:
eng 
Print-ISSN:
0147-5185 
TUM Institution:
Institut für Allgemeine Pathologie und pathologische Anatomie