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Document type:
journal article 
Author(s):
Walch, A; Seidl, S; Hermannstädter, C; Rauser, S; Deplazes, J; Langer, R; von Weyhern, CH; Sarbia, M; Busch, R; Feith, M; Gillen, S; Höfler, H; Luber, B 
Title:
Combined analysis of Rac1, IQGAP1, Tiam1 and E-cadherin expression in gastric cancer. 
Abstract:
Rho GTPases are a family of major regulators of E-cadherin-mediated cell adhesion that are implicated in the carcinogenic process by deregulated expression of the family members itself or of upstream modulators or downstream effectors. Combined investigation of the Rho GTPase Rac1, the effector protein IQGAP1 and the activator Tiam1 in relation to expression or mutation of E-cadherin in gastric adenocarcinomas has not been reported. The aim of the study was to determine the expression and progno...    »
 
Journal title abbreviation:
Mod Pathol 
Year:
2008 
Journal volume:
21 
Journal issue:
Pages contribution:
544-52 
Language:
eng 
Print-ISSN:
0893-3952 
TUM Institution:
Institut für Allgemeine Pathologie und pathologische Anatomie ; Institut für Medizinische Statistik und Epidemiologie ; Chirurgiesche Klinik und Poliklinik