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Dokumenttyp:
journal article 
Autor(en):
Walch, A; Seidl, S; Hermannstädter, C; Rauser, S; Deplazes, J; Langer, R; von Weyhern, CH; Sarbia, M; Busch, R; Feith, M; Gillen, S; Höfler, H; Luber, B 
Titel:
Combined analysis of Rac1, IQGAP1, Tiam1 and E-cadherin expression in gastric cancer. 
Abstract:
Rho GTPases are a family of major regulators of E-cadherin-mediated cell adhesion that are implicated in the carcinogenic process by deregulated expression of the family members itself or of upstream modulators or downstream effectors. Combined investigation of the Rho GTPase Rac1, the effector protein IQGAP1 and the activator Tiam1 in relation to expression or mutation of E-cadherin in gastric adenocarcinomas has not been reported. The aim of the study was to determine the expression and progno...    »
 
Zeitschriftentitel:
Mod Pathol 
Jahr:
2008 
Band / Volume:
21 
Heft / Issue:
Seitenangaben Beitrag:
544-52 
Sprache:
eng 
Print-ISSN:
0893-3952 
TUM Einrichtung:
r Allgemeine Pathologie und pathologische Anatomie; r Medizinische Statistik und Epidemiologie; Chirurgiesche Klinik und Poliklinik