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Document type:
journal article 
Author(s):
Mello, ML; Vidal, BC; Russo, J; Planding, W; Schenck, U 
Title:
Image analysis of the AgNOR response in ras-transformed human breast epithelial cells. 
Abstract:
The argyrophylic staining of the nucleolar organizer regions (AgNOR positive response) in interphase nuclei is often related directly to the cellular demand for ribosome biogenesis and is considered of relevance in studies of tumor pathology. Transformation of human breast epithelial MCF-10A cells by the c-Ha-ras oncogene results in altered growth, invasiveness and tumorigenicity in nude mice. Since ras transformation may be associated with a more intense nucleolar activity, we examined the infl...    »
 
Journal title abbreviation:
Acta Histochem 
Year:
2008 
Journal volume:
110 
Journal issue:
Pages contribution:
210-6 
Language:
eng 
Print-ISSN:
0065-1281 
TUM Institution:
Institut für Allgemeine Pathologie und pathologische Anatomie