Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Anlauf, M; Perren, A; Klöppel, G 
Titel:
[Gastrin cell hyperplasia associated with duodenal MEN1-related gastrinomas: histopathology and genetics] 
Abstract:
AIMS: The identification of precursor lesions has a great impact on our understanding of tumorigenesis. In this study we investigated whether preneoplastic lesions can be identified in sporadic gastrinomas and in gastrinomas in multiple endocrine neoplasia type 1 (MEN1) patients. These lesions were tested for loss of heterozygosity (LOH) of the MEN1 gene locus on chromosome 11q13. MATERIAL AND METHODS: Tissue specimens from 25 patients with Zollinger-Ellison syndrome (ZES) were analyzed. The MEN...    »
 
Zeitschriftentitel:
Verh Dtsch Ges Pathol 
Jahr:
2007 
Band / Volume:
91 
Seitenangaben Beitrag:
320-9 
Sprache:
de 
Print-ISSN:
0070-4113 
TUM Einrichtung:
r Allgemeine Pathologie und pathologische Anatomie