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Document type:
journal article 
Author(s):
Blechschmidt, K; Kremmer, E; Hollweck, R; Mylonas, I; Höfler, H; Kremer, M; Becker, KF 
Title:
The E-cadherin Repressor Snail Plays a Role in Tumor Progression of Endometrioid Adenocarcinomas. 
Abstract:
Endometrial cancer is the most common gynecologic cancer in the developed world. The cell-adhesion protein E-cadherin acts as a tumor-suppressor protein and is down-regulated by the transcription factor Snail, whose expression was shown to be associated with estrogen receptor signaling. This study aimed to investigate the expression of E-cadherin, Snail, and estrogen-receptor alpha in 87 primary tumors and 26 metastases of endometroid endometrial carcinomas. Reduced E-cadherin immunoreactivity w...    »
 
Journal title abbreviation:
Diagn Mol Pathol 
Year:
2007 
Journal volume:
16 
Journal issue:
Pages contribution:
222-228 
Language:
eng 
Print-ISSN:
1052-9551 
TUM Institution:
Institut für Allgemeine Pathologie und pathologische Anatomie