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Dokumenttyp:
journal article 
Autor(en):
Korpershoek, E; Petri, BJ; van Nederveen, FH; Dinjens, WN; Verhofstad, AA; de Herder, WW; Schmid, S; Perren, A; Komminoth, P; de Krijger, RR 
Titel:
Candidate gene mutation analysis in bilateral adrenal pheochromocytoma and sympathetic paraganglioma. 
Abstract:
Pheochromocytomas (PCCs) are rare tumors that arise from chromaffin tissue in the adrenal medulla, but can also occur in the abdomen outside the adrenals and are then called sympathetic paragangliomas (sPGLs). According to the literature, between 15 and 25% of apparently sporadic adrenal PCC and sPGL are caused by germline mutations in RET, von Hippel-Lindau disease (VHL), succinate dehydrogenase subunit B (SDHB), or subunit D SDHD. However, few studies have addressed the mutationfrequency of th...    »
 
Zeitschriftentitel:
Endocr Relat Cancer 
Jahr:
2007 
Band / Volume:
14 
Heft / Issue:
Seitenangaben Beitrag:
453-62 
Sprache:
eng 
Print-ISSN:
1351-0088 
TUM Einrichtung:
r Allgemeine Pathologie und pathologische Anatomie