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Dokumenttyp:
journal article 
Autor(en):
Breunig, E; Michel, K; Zeller, F; Seidl, S; Weyhern, CW; Schemann, M 
Titel:
Histamine excites neurones in the human submucous plexus through activation of H1, H2, H3 and H4 receptors. 
Abstract:
Histamine is a major mast cell mediator of immunoneural signalling in the gut and mast cells play a role in the pathophysiology of functional and inflammatory bowel diseases. Histamine receptors are therefore promising drug targets to treat gut disorders. We aimed to study the so far unknown effect of histamine on neural activity in the human enteric nervous system (ENS) and to identify the pharmacology of histamine response. We used fast imaging techniques in combination with the potentiometric...    »
 
Zeitschriftentitel:
J Physiol 
Jahr:
2007 
Band / Volume:
583 
Heft / Issue:
Pt 2 
Seitenangaben Beitrag:
731-42 
Sprache:
eng 
Print-ISSN:
0022-3751 
TUM Einrichtung:
r Allgemeine Pathologie und pathologische Anatomie