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Document type:
journal article 
Author(s):
Beaufort, N; Leduc, D; Eguchi, H; Mengele, K; Hellmann, D; Masegi, T; Kamimura, T; Yasuoka, S; Fend, F; Chignard, M; Pidard, D 
Title:
The human airway trypsin-like protease modulates the urokinase receptor (uPAR, CD87) structure and functions. 
Abstract:
The human airway trypsin-like protease (HAT) is a respiratory epithelium-associated, type II transmembrane serine protease, which is also detected as an extracellular enzyme in lung fluids during airway inflammatory disorders. We have evaluated its capacity to affect the urokinase-type plasminogen activator receptor (uPAR), a membrane glycolipid-anchored, three-domain (D1D2D3) glycoprotein that plays a crucial role in innate immunity and inflammation by supporting cell migration and matrix degra...    »
 
Journal title abbreviation:
Am J Physiol Lung Cell Mol Physiol 
Year:
2007 
Journal volume:
292 
Journal issue:
Pages contribution:
L1263-72 
Language:
eng 
Print-ISSN:
1040-0605 
TUM Institution:
Frauenklinik und Poliklinik; r Allgemeine Pathologie und pathologische Anatomie