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Document type:
journal article 
Author(s):
Spuentrup, E; Katoh, M; Wiethoff, AJ; Buecker, A; Botnar, RM; Parsons, EC; Guenther, RW 
Title:
Molecular coronary MR imaging of human thrombi using EP-2104R, a fibrin-targeted contrast agent: experimental study in a swine model. 
Abstract:
PURPOSE: The aim of this study was to investigate the use of a fibrin-specific contrast agent (EP-2104R, EPIX Pharmaceuticals, Lexington, Massachusetts, USA) for targeted molecular magnetic resonance (MR) imaging of human clot material removed from patients in a model of coronary thrombosis in swine. MATERIALS AND METHODS: Freshly ex vivo engineered clots from human blood and human in situ developed clots removed from patients were delivered into the coronary arteries of nine domestic swine. For...    »
 
Journal title abbreviation:
Rofo 
Year:
2007 
Journal volume:
179 
Journal issue:
11 
Pages contribution:
1166-73 
Language:
eng 
Print-ISSN:
1438-9029 
TUM Institution:
Nuklearmedizinische Klinik und Poliklinik