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Dokumenttyp:
journal article 
Autor(en):
Makrides, V; Bauer, R; Weber, W; Wester, HJ; Fischer, S; Hinz, R; Huggel, K; Opfermann, T; Herzau, M; Ganapathy, V; Verrey, F; Brust, P 
Titel:
Preferred transport of O-(2-[18F]fluoroethyl)-D-tyrosine (D-FET) into the porcine brain. 
Abstract:
Amino acids are valuable tracers for brain tumor imaging with positron emission tomography (PET). In this study the transport of O-(2-[(18)F]fluoroethyl)-D-tyrosine (D-FET) across the blood-brain barrier (BBB) was studied with PET in anesthetized piglets and patients after subtotal resection of brain tumors and compared with O-(2-[(18)F]fluoroethyl)-L-tyrosine (L-FET) and 3-O-methyl-6-[(18)F]fluoro-L-DOPA (L-OMFD). In piglets, compartmental modeling of PET data was used to calculate the rate con...    »
 
Zeitschriftentitel:
Brain Res 
Jahr:
2007 
Band / Volume:
1147 
Seitenangaben Beitrag:
25-33 
Sprache:
eng 
Print-ISSN:
0006-8993 
TUM Einrichtung:
Nuklearmedizinische Klinik und Poliklinik