Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Kemlink, D; Plazzi, G; Vetrugno, R; Provini, F; Polo, O; Stiasny-Kolster, K; Oertel, W; Nevsimalova, S; Sonka, K; Högl, B; Frauscher, B; Hadjigeorgiou, GM; Pramstaller, PP; Lichtner, P; Meitinger, T; Müller-Myshok, B; Winkelmann, J; Montagna, P 
Titel:
Suggestive evidence for linkage for restless legs syndrome on chromosome 19p13. 
Abstract:
Five loci for restless legs syndrome (RLS) on chromosomes 12q, 14q, 9p, 2q, and 20p (RLS1-RLS5) have been mapped in RLS families, with a recessive in the first and autosomal-dominant mode of inheritance in the latter cases. Investigations of further RLS families showed evidence for genetic locus heterogeneity. We have conducted a genome-wide linkage analysis in a large RLS family of Italian origin with 12 affected members in 3 generations using 5,861 single nucleotide polymorphisms (SNP, 6K Illu...    »
 
Zeitschriftentitel:
Neurogenetics 
Jahr:
2008 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
75-82 
Sprache:
eng 
Print-ISSN:
1364-6745 
TUM Einrichtung:
r Humangenetik; Neurologische Klinik und Poliklinik