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Document type:
journal article 
Author(s):
Vollmar, P; Haghikia, A; Dermietzel, R; Faustmann, PM 
Title:
Venlafaxine exhibits an anti-inflammatory effect in an inflammatory co-culture model. 
Abstract:
Growing evidence indicates immunoregulatory effects of various antidepressants. Through the interaction of the nervous and immune systems, the norepinephrine-serotonin system was shown to modulate inflammatory CNS diseases. Thus, we examined the norepinephrine-serotonin reuptake inhibitor venlafaxine in an astroglia-microglia co-culture model which allows mimicking of an inflammatory milieu by increasing the cultured microglial fraction. Astrocytic membrane resting potential and intercellular co...    »
 
Journal title abbreviation:
Int J Neuropsychopharmacol 
Year:
2008 
Journal volume:
11 
Journal issue:
Pages contribution:
111-7 
Language:
eng 
Print-ISSN:
1461-1457 
TUM Institution:
Neurologische Klinik und Poliklinik