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Document type:
journal article 
Author(s):
Timmermann, L; Braun, M; Groiss, S; Wojtecki, L; Ostrowski, S; Krause, H; Pollok, B; Südmeyer, M; Ploner, M; Gross, J; Maarouf, M; Voges, J; Sturm, V; Schnitzler, A 
Title:
Differential effects of levodopa and subthalamic nucleus deep brain stimulation on bradykinesia in Parkinson's disease. 
Abstract:
Cardinal symptoms of Parkinson's disease (PD) respond well to treatment with levodopa and deep brain stimulation (DBS) of the subthalamic nucleus (STN). However, it has remained unclear whether levodopa and STN-DBS have differential effects on bradykinesia. We investigated 8 PD-patients with STN-electrodes in four conditions: STN-DBS and levodopa (ON(MED)/ON(STIM)), STN-DBS only (OFF(MED)/ON(STIM)), levodopa only (ON(MED)/OFF(STIM)), without STN-DBS/levodopa (OFF(MED)/OFF(STIM)). Fourteen volunt...    »
 
Journal title abbreviation:
Mov Disord 
Year:
2008 
Journal volume:
23 
Journal issue:
Pages contribution:
218-27 
Language:
eng 
Print-ISSN:
0885-3185 
TUM Institution:
Neurologische Klinik und Poliklinik