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Dokumenttyp:
journal article 
Autor(en):
Timmermann, L; Braun, M; Groiss, S; Wojtecki, L; Ostrowski, S; Krause, H; Pollok, B; Südmeyer, M; Ploner, M; Gross, J; Maarouf, M; Voges, J; Sturm, V; Schnitzler, A 
Titel:
Differential effects of levodopa and subthalamic nucleus deep brain stimulation on bradykinesia in Parkinson's disease. 
Abstract:
Cardinal symptoms of Parkinson's disease (PD) respond well to treatment with levodopa and deep brain stimulation (DBS) of the subthalamic nucleus (STN). However, it has remained unclear whether levodopa and STN-DBS have differential effects on bradykinesia. We investigated 8 PD-patients with STN-electrodes in four conditions: STN-DBS and levodopa (ON(MED)/ON(STIM)), STN-DBS only (OFF(MED)/ON(STIM)), levodopa only (ON(MED)/OFF(STIM)), without STN-DBS/levodopa (OFF(MED)/OFF(STIM)). Fourteen volunt...    »
 
Zeitschriftentitel:
Mov Disord 
Jahr:
2008 
Band / Volume:
23 
Heft / Issue:
Seitenangaben Beitrag:
218-27 
Sprache:
eng 
Print-ISSN:
0885-3185 
TUM Einrichtung:
Neurologische Klinik und Poliklinik