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Dokumenttyp:
journal article 
Autor(en):
Michalke, B; Berthele, A; Mistriotis, P; Ochsenkühn-Petropoulou, M; Halbach, S 
Titel:
Manganese speciation in human cerebrospinal fluid using CZE coupled to inductively coupled plasma MS. 
Abstract:
The neurotoxic effects of manganese (Mn) at elevated concentrations are well known. This raises the question, which of the Mn species can cross neural barriers and appear in cerebrospinal fluid (CSF). CSF is the last matrix in a living human organism available for analysis before a compound reaches the brain cells and therefore it is assumed to reflect best the internal exposure of brain tissue to Mn species. A previously developed CE method was modified for separation of albumin, histidine, tyr...    »
 
Zeitschriftentitel:
Electrophoresis 
Jahr:
2007 
Band / Volume:
28 
Heft / Issue:
Seitenangaben Beitrag:
1380-6 
Sprache:
eng 
Print-ISSN:
0173-0835 
TUM Einrichtung:
Neurologische Klinik und Poliklinik