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Document type:
journal article 
Author(s):
Mages, J; Dietrich, H; Lang, R 
Title:
A genome-wide analysis of LPS tolerance in macrophages. 
Abstract:
Among the multiple mechanisms that control the intensity and duration of macrophage activation, the development of a state of refractoriness to a second stimulation in cells treated with lipopolysaccharide (LPS) has long been recognized. Release of inhibitory cytokines and alterations in intracellular signaling pathways may be involved in the development of LPS tolerance. Although a number of molecules have been implicated, a detailed picture of the molecular changes in LPS tolerance is still mi...    »
 
Journal title abbreviation:
Immunobiology 
Year:
2007 
Journal volume:
212 
Journal issue:
9-10 
Pages contribution:
723-37 
Language:
eng 
Print-ISSN:
0171-2985 
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene