User: Guest  Login
Document type:
journal article 
Author(s):
Häcker, G; Weber, A 
Title:
BH3-only proteins trigger cytochrome c release, but how? 
Abstract:
The mitochondrial apoptosis pathway has been neatly ordered. Mitochondrial apoptosis is governed by Bcl-2 family proteins, and their respective contributions determine the release of cytochrome c. It is clear that, among the Bcl-2 family, BH3-only proteins are the triggers: activation of BH3-only proteins by apoptotic stimuli initiates the process. BH3-only proteins cause cytochrome c release by activating Bax and/or Bak, and the anti-apoptotic group of Bcl-2-like proteins prevents this. However...    »
 
Journal title abbreviation:
Arch Biochem Biophys 
Year:
2007 
Journal volume:
462 
Journal issue:
Pages contribution:
150-5 
Language:
eng 
Print-ISSN:
0003-9861 
TUM Institution:
r Medizinische Mikrobiologie, Immunologie und Hygiene