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Dokumenttyp:
journal article 
Autor(en):
Häcker, G; Weber, A 
Titel:
BH3-only proteins trigger cytochrome c release, but how? 
Abstract:
The mitochondrial apoptosis pathway has been neatly ordered. Mitochondrial apoptosis is governed by Bcl-2 family proteins, and their respective contributions determine the release of cytochrome c. It is clear that, among the Bcl-2 family, BH3-only proteins are the triggers: activation of BH3-only proteins by apoptotic stimuli initiates the process. BH3-only proteins cause cytochrome c release by activating Bax and/or Bak, and the anti-apoptotic group of Bcl-2-like proteins prevents this. However...    »
 
Zeitschriftentitel:
Arch Biochem Biophys 
Jahr:
2007 
Band / Volume:
462 
Heft / Issue:
Seitenangaben Beitrag:
150-5 
Sprache:
eng 
Print-ISSN:
0003-9861 
TUM Einrichtung:
r Medizinische Mikrobiologie, Immunologie und Hygiene