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Dokumenttyp:
journal article 
Autor(en):
Spiller, S; Dreher, S; Meng, G; Grabiec, A; Thomas, W; Hartung, T; Pfeffer, K; Hochrein, H; Brade, H; Bessler, W; Wagner, H; Kirschning, CJ 
Titel:
Cellular recognition of trimyristoylated peptide or enterobacterial lipopolysaccharide via both TLR2 and TLR4. 
Abstract:
Evidence for specific and direct bacterial product recognition through toll-like receptors (TLRs) has been emphasized recently. We analyzed lipopeptide analogues and enterobacterial lipopolysaccharide (eLPS) for their potential to activate cells through TLR2 and TLR4. Whereas bacterial protein palmitoylated at its N-terminal cysteine and N-terminal peptides derived thereof are known to induce TLR2-mediated cell activation, a synthetic acylhexapeptide mimicking a bacterial lipoprotein subpopulati...    »
 
Zeitschriftentitel:
J Biol Chem 
Jahr:
2007 
Band / Volume:
282 
Heft / Issue:
18 
Seitenangaben Beitrag:
13190-8 
Sprache:
eng 
Print-ISSN:
0021-9258 
TUM Einrichtung:
r Medizinische Mikrobiologie, Immunologie und Hygiene