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Document type:
journal article 
Author(s):
Rosenberg, R; Nekarda, H; Zimmermann, F; Becker, K; Lordick, F; Hofler, H; Molls, M; Siewert, JR 
Title:
Histopathological response after preoperative radiochemotherapy in rectal carcinoma is associated with improved overall survival. 
Abstract:
BACKGROUND: Recent studies showed improved local control after preoperative radiochemotherapy (RCTX) in patients with locally advanced rectal carcinoma, but failed to demonstrate a survival benefit. Our aims were to determine outcome and impact of histopathological response after preoperative RCTX. METHODS: One hundred four patients with uT3 rectal carcinoma were treated with preoperative RCTX of 45 Gy and continuous 5-FU infusion between 1997 and 2001 (group I). Histopathological response was e...    »
 
Journal title abbreviation:
J Surg Oncol 
Year:
2008 
Journal volume:
97 
Journal issue:
Pages contribution:
8-13 
Language:
eng 
Print-ISSN:
0022-4790 
TUM Institution:
Chirurgiesche Klinik und Poliklinik; r Allgemeine Pathologie und pathologische Anatomie; III. Medizinische Klinik und Poliklinik; r Strahlentherapie und Radiologische Onkologie